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methylprednisolone will lower the level or impact of triazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.bosentan will lessen the level or outcome of triazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.Keep an eye on Intently (one)mitotane decreases amounts of tri